Correlation of Serum Vitamin A Levels with Disease Activity Indices and Colonic IL-23R and FOXP3 mRNA Expression in Ulcerative Colitis Patients
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چکیده
منابع مشابه
Evaluation of the relationship between serum vitamin D levels and disease recurrence in patients with ulcerative colitis
Background: one of the growing diseases in the world that affects patient life quality is Inflammatory bowel disease (IBD), including ulcerative colitis (UC). Many environmental factors, including nutritional deficiencies, may influence the development of the disease. This study aims to evaluate the role of the level of vitamin D in UC recurrence. Methods: We performed this cross-sectional stu...
متن کاملSerum Interleukin-23 Levels in Patients with Ulcerative Colitis
Background: Patients with ulcerative colitis are at increased risk of inflammation. Interleukin 23 (IL-23) is a newly identified cytokine with increased expression in inflamed biopsies of colon mucosa in patients with Crohn's disease; however, there is inconsistent evidence on its role in ulcerative colitis. Objective: We aimed to compare serum IL-23 level in patients with ulcerative colitis an...
متن کاملInterleukin-17 Serum Levels and TLR4 Polymorphisms in Ulcerative Colitis
Background: Inflammatory bowel disease, an autoimmune disease, has two clinical manifestations including Crohn’s disease and ulcerative colitis (UC). IL-17 has been the target of intensive research in autoimmune diseases. The influence of Toll like receptor 4 (TLR-4) gene polymorphisms on IL-17 production has also been revealed in UC patients and tissue inflammation in mice. Objectives: To inve...
متن کاملElevated IL-23R Expression and Foxp3+Rorγt+ Cells in Intestinal Mucosa During Acute and Chronic Colitis
BACKGROUND IL-23/IL-23R signaling plays a pivotal role during the course of inflammatory bowel diseases (IBD). However, the underlying mechanisms are poorly characterized. Foxp3+ regulatory T cells are critical in the maintenance of gut immune homeostasis and therefore are important in preventing the development of IBD. This study was performed to clarify the association between IL-23/IL-23R si...
متن کاملCorrelation between Serum Levels of Calprotectin with Disease Activity in Rheumatoid Arthritis Patients
Background and Objective: Rheumatoid arthritis (RA) is an autoimmune disease defined by chronic synovitis and progressive joint destruction. This study investigated calprotectin as a serological marker in the hope of establishing an adequate means of diagnosing RA and following up on patients. Materials and Methods: This cross-sectional study included 32 RA patients who were referred to the rh...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Immunology
سال: 2016
ISSN: 0300-9475
DOI: 10.1111/sji.12450